Manny Pacquiao steps back into the boxing ring this Saturday night in Las Vegas, ending a nearly four-year hiatus at the age of 46. The Filipino legend will challenge Mario Barrios for the WBC welterweight championship in what many consider an uphill battle against time and boxing logic.

The eight-division world champion hasn't fought professionally since 2021, raising questions about his ability to compete at the highest level despite his storied career.

"Coming back at this age is challenging, but I've never backed down from a fight," Pacquiao might say about his unexpected return.

Despite Barrios not being considered among boxing's elite champions, a victory for Pacquiao would register as a massive upset given his advanced age and extended time away from competitive fighting.

Pacquiao's legendary career includes numerous defining moments across multiple weight classes. His 2009 dismantling of Miguel Cotto stands as perhaps his greatest performance, when he secured a 12th-round TKO to claim the WBO welterweight title after dropping the Puerto Rican in rounds three and four.

Worth noting, Pacquiao's explosive 2003 victory over Marco Antonio Barrera marked his arrival as a global boxing star, dominating the then-Ring Magazine featherweight champion despite being considered an underdog.

Fans still remember his shocking second-round knockout of Ricky Hatton in 2009, when Pacquiao unleashed what many call the "left hook from hell" to instantly end the contest against the previously undefeated light-welterweight champion.

Interestingly, what should have been Pacquiao's perfect farewell came in 2016 against Tim Bradley, when he dropped his opponent twice en route to a unanimous decision victory. He promised retirement afterward but returned just seven months later to face Jessie Vargas.

Pacquiao's division-jumping exploits began in earnest with his 2008 dismantling of David Diaz for the lightweight title, marking the start of his imperial period where he would collect belts across heavier weight classes.

Can the aging legend summon enough of his former brilliance to overcome a younger champion? Saturday night will determine if there's one more chapter to be written in boxing's most remarkable career.